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Article

Role of histone deacetylases in pancreas: Implications for pathogenesis and therapy

1 Jan 2015

Abstract excerpt

In the last years, our knowledge of the pathogenesis in acute and chronic pancreatitis (AP/CP) as well as in pancreatic cancerogenesis has significantly diversified. Nevertheless, the medicinal therapeutic options are still limited and therapeutic success and patient outcome are poor. Epigenetic deregulation of gene expression is known to contribute to development and progression of AP and CP as well as of...

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PMID: 26691388
DOI: 10.4251/wjgo.v7.i12.473

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