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Exploring histone deacetylases in type 2 diabetes mellitus: pathophysiological insights and therapeutic avenues

11 Jun 2024

Abstract excerpt

Diabetes mellitus is a chronic disease that impairs metabolism, and its prevalence has reached an epidemic proportion globally. Most people affected are with type 2 diabetes mellitus (T2DM), which is caused by a decline in the numbers or functioning of pancreatic endocrine islet cells, specifically the β-cells that release insulin in sufficient quantity to overcome any insulin resistance of the metabolic tissues....

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PMID: 38862980
DOI: 10.1186/s13148-024-01692-0

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