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Histone deacetylases and inhibitors in diabetes mellitus and its complications

26 Jun 2024

Abstract excerpt

Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia, with its prevalence linked to both genetic predisposition and environmental factors. Epigenetic modifications, particularly through histone deacetylases (HDACs), have been recognized for their significant influence on DM pathogenesis. This review focuses on the classification of HDACs, their role in DM and its complications, and the...

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PMID: 38941890
DOI: 10.1016/j.biopha.2024.117010

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