Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic targeting in pancreatic cancer

4 Jan 2014

Abstract excerpt

The prognosis of pancreatic cancer patients is very poor, with a 5-year survival of less than 6%. Therefore, there is an urgent need for new therapeutic options in pancreatic cancer. In the past years it became evident that deregulation of epigenetic mechanisms plays an important role in pancreatic carcinogenesis. This review focuses on the exploitation of drugs that alter histone modifications, DNA methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Histone Deacetylase Inhibitors Research
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24433955
DOI: 10.1016/j.ctrv.2013.12.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic targeting in pancreatic cancerPMID 24433955Read ↗

Epigenetics and pancreatic cancer: pathophysiology and novel treatment aspects.Semantic proximity Read ↗

Advances in pancreatic cancer epigenetics: From the mechanism to the clinicSemantic proximity Read ↗

Alteration of Epigenetic Modifiers in Pancreatic Cancer and Its Clinical ImplicationSemantic proximity Read ↗

Histone methylation in pancreatic cancer and its clinical implicationsSemantic proximity Read ↗

The role of epigenetic alterations in pancreatic cancerSemantic proximity Read ↗

Epigenetic Targeting of Aberrant Transcriptional Modulation in Pancreatic CancerSemantic proximity Read ↗

Epigenetics in Pancreatic Ductal Adenocarcinoma: Impact on Biology and Utilization in Diagnostics and TreatmentSemantic proximity Read ↗

Epigenetic reprogramming in pancreatic premalignancy and clinical implicationsSemantic proximity Read ↗

An overview of genetic mutations and epigenetic signatures in the course of pancreatic cancer progression.Semantic proximity Read ↗

Histone Modifications Represent a Key Epigenetic Feature of Epithelial-to-Mesenchyme Transition in Pancreatic CancerSemantic proximity Read ↗

DNMT1 as a therapeutic target in pancreatic cancer: mechanisms and clinical implicationsSemantic proximity Read ↗

Genetic and Epigenetic Alterations in Pancreatic CarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.