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Article

Combined effect of genetic variants in the GluN2B coding gene (GRIN2B) on prefrontal function during working memory performance.

Psychological medicine - 1 Apr 2016

Pergola G, Di Carlo P, Andriola I, Gelao B, Torretta S, Attrotto M T, Fazio L, Raio A, Albergo D, Masellis R, Rampino A, Blasi G, Bertolino A

Abstract excerpt

BACKGROUND: The GluN2B subunit of N-methyl-d-aspartate receptors is crucially involved in the physiology of the prefrontal cortex during working memory (WM). Consistently, genetic variants in the GluN2B coding gene (GRIN2B) have been associated with cognitive phenotypes. However, it is unclear how GRIN2B genetic variation affects gene expression and prefrontal cognitive processing. Using a composite score, we...

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Identifiers

PMID: 26690829
DOI: 10.1017/S0033291715002639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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