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Article

GRIN2B gene and associated brain cortical white matter changes in bipolar disorder: a preliminary combined platform investigation.

BioMed research international - 1 Jan 2013

Kuswanto Carissa Nadia, Sum Min Yi, Thng Christopher Ren Zhi, Zhang Yi Bin, Yang Guo Liang, Nowinski Wieslaw Lucjan, Sitoh Yih Yian, Low Chian Ming, Sim Kang

Abstract excerpt

Abnormalities in glutamate signaling and glutamate toxicity are thought to be important in the pathophysiology of bipolar disorder (BD). Whilst previous studies have found brain white matter changes in BD, there is paucity of data about how glutamatergic genes affect brain white matter integrity in BD. Based on extant neuroimaging data, we hypothesized that GRIN2B risk allele is associated with reductions of...

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Identifiers

PMID: 24490167
DOI: 10.1155/2013/635131
PMCID: PMC3893811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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