Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dopamine D4 receptor VNTR polymorphism associated with greater risk for substance abuse among adolescents with disruptive behavior disorders: Preliminary results.

The American journal on addictions - 1 Jan 2016

Mallard Travis T, Doorley James, Esposito-Smythers Christianne L, McGeary John E

Abstract excerpt

BACKGROUND AND OBJECTIVES: The variable number tandem repeats (VNTR) polymorphism of the dopamine D4 receptor gene (DRD4) has received considerable attention as a potential genetic contributor to addiction. However, is unclear whether the polymorphism is involved in developing general traits that lead to risky behavior or an intermediate phenotype more specific to substance use disorders. Association studies have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Attention Deficit and Disruptive Behavior Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Heterozygote

Share to Minisatellite Repeats

Share to Polymorphism, Genetic

Share to Receptors, Dopamine D4

Share to Substance-Related Disorders

Source

Identifiers

PMID: 26688118
DOI: 10.1111/ajad.12320

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dopamine D4 receptor VNTR polymorphism associated with greater risk for substance abuse among adolescents with disruptive behavior disorders: Preliminary results.PMID 26688118Read ↗

Associations of the dopamine D4 receptor gene VNTR polymorphism with drug use in adolescent psychiatric inpatients.Semantic proximity Read ↗

Dopamine receptor (D4) polymorphism is related to comorbidity between marijuana abuse and depression.Semantic proximity Read ↗

Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene.Semantic proximity Read ↗

Underlying Susceptibility to Eating Disorders and Drug Abuse: Genetic and Pharmacological Aspects of Dopamine D4 Receptors.Semantic proximity Read ↗

Studies of the 48 bp repeat polymorphism of the DRD4 gene in impulsive, compulsive, addictive behaviors: Tourette syndrome, ADHD, pathological gambling, and substance abuse.Semantic proximity Read ↗

Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: results from a high-risk community sample.Semantic proximity Read ↗

Dopamine D2 receptor gene polymorphisms and vulnerability to substance abuse in African Americans.Semantic proximity Read ↗

Epistatic interactions involving DRD2, DRD4, and COMT polymorphisms and risk of substance abuse in women with binge-purge eating disturbances.Semantic proximity Read ↗

Associations of the DRD2 TaqIA polymorphism with impulsivity and substance use: preliminary results from a clinical sample of adolescents.Semantic proximity Read ↗

Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders.Semantic proximity Read ↗

DRD2 genotypes and substance use in adolescent children of alcoholics.Semantic proximity Read ↗

Gene-environment interaction in problematic substance use: interaction between DRD4 and insecure attachments.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.