Article
Associations of the DRD2 TaqIA polymorphism with impulsivity and substance use: preliminary results from a clinical sample of adolescents.
Pharmacology, biochemistry, and behavior - 1 Sept 2009
Esposito-Smythers Christianne, Spirito Anthony, Rizzo Christie, McGeary John E, Knopik Valerie S
Abstract excerpt
BACKGROUND: The A1 allele of the TaqIA polymorphism (rs1800497) in the dopamine D2 receptor gene (DRD2) has been associated with substance use. It is unclear whether this allele is a marker for an underlying propensity for specifically developing a substance use disorder, or more generally to developing an externalizing psychiatric disorder highly correlated with substance use. It is also possible that DRD2 is...
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