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Article

Gene-environment interaction in problematic substance use: interaction between DRD4 and insecure attachments.

Addiction biology - 1 Jul 2013

Olsson Craig A, Moyzis Robert K, Williamson Elizabeth, Ellis Justine A, Parkinson-Bates Mandy, Patton George C, Dwyer Terry, Romaniuk Helena, Moore Elya E

Abstract excerpt

To investigate the combined effect of an exon III variable number tandem repeat in the dopamine receptor gene (DRD4) and insecure attachment style on risk for tobacco, cannabis and alcohol use problems in young adulthood. It was hypothesized that (1) individuals with 5, 6, 7 or 8 repeats (labelled 7R+) would be at increased risk for problematic drug use, and (2) risk for drug use would be further increased in...

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Source

Identifiers

PMID: 22126256
DOI: 10.1111/j.1369-1600.2011.00413.x

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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