Article
DRD2 genotypes and substance use in adolescent children of alcoholics.
Drug and alcohol dependence - 1 Sept 2005
Conner Bradley T, Noble Ernest P, Berman Steven M, Ozkaragoz Tulin, Ritchie Terry, Antolin Tim, Sheen Courtney
Abstract excerpt
Research has identified children of alcoholics (COAs) as a population at increased risk for developing substance use problems. Genetic studies support the Al allele of the D2 dopamine receptor gene (DRD2) as a risk marker for alcoholism and substance use disorders. In this study, substance use was assessed in 48 adolescent boys of alcoholics with the DRDR A1(+) allele (A1A1/A1A2 genotypes) or the A1(-) allele...
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