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Article

Genetic variant of the renin-angiotensin system and prevalence of type 2 diabetes mellitus: a modest but significant effect of aldosterone synthase.

Acta diabetologica - 1 Aug 2014

Ichikawa Mai, Konoshita Tadashi, Nakaya Takahiro, Yamamoto Katsushi, Yamada Mika, Sato Satsuki, Imagawa Michiko, Makino Yasukazu, Fujii Miki, Zenimaru Yasuo, Arakawa Kenichiro, Suzuki Jinya, Ishizuka Tamotsu, Nakamura Hiroyuki

Abstract excerpt

Recent genome-wide association studies have identified multiple variants that confer risk of type 2 diabetes mellitus (DM). However, established associations explain only a part of the heritability. Thus, even at the genome-wide association studies era, candidate gene approach should be still use...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24549414
DOI: 10.1007/s00592-014-0561-7
PMCID: PMC4127438

Genes

ACE
AGT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24549414-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Genetic variant of the renin-angiotensin system and prevalence of type 2 diabetes mellitus: a modest but significant effect of aldosterone synthase.PMID 24549414Read ↗

Renin-Angiotensin System Gene Variants and Type 2 Diabetes Mellitus: Influence of Angiotensinogen.Semantic proximity Read ↗

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Associations of the -344 T>C and the 3097 G>A polymorphisms of CYP11B2 gene with hypertension, type 2 diabetes, and metabolic syndrome in a French population.Semantic proximity Read ↗

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