Article
Meta-analytic research on the relationship between cumulative risk alleles and risk of type 2 diabetes mellitus.
Diabetes/metabolism research and reviews - 1 Feb 2016
Kodama Satoru, Fujihara Kazuya, Ishiguro Hajime, Horikawa Chika, Ohara Nobumasa, Yachi Yoko, Tanaka Shiro, Shimano Hitoshi, Kato Kiminori, Hanyu Osamu, Sone Hirohito
Abstract excerpt
BACKGROUND: Our aim is to examine the dose-response association between cumulative genetic risk and actual risk of type 2 diabetes mellitus (T2DM) and the influence of adjustment for covariates on T2DM risk through a comprehensive meta-analysis of observational studies. METHODS: Electronic literature search using EMBASE and MEDLINE (from 2003 to 2014) was conducted for cross-sectional or longitudinal studies that...
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