Article
Angiotensin II type 1 receptor polymorphisms and susceptibility to hypertension: a HuGE review.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Aug 2008
Mottl Amy K, Shoham David A, North Kari E
Abstract excerpt
The angiotensin II type 1 receptor (AGTR1) plays an integral role in blood pressure control, and is implicated in the pathogenesis of hypertension. Polymorphisms within this gene have been extensively studied in association with hypertension; however, findings are conflicting. To clarify these data, we conducted a systematic review of association studies of AGTR1 polymorphisms and hypertension, and performed a...
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