Article
ARG-walker: inference of individual specific strengths of meiotic recombination hotspots by population genomics analysis.
BMC genomics - 1 Jan 2015
Chen Hao, Yang Peng, Guo Jing, Kwoh Chee Keong, Przytycka Teresa M, Zheng Jie
Abstract excerpt
BACKGROUND: Meiotic recombination hotspots play important roles in various aspects of genomics, but the underlying mechanisms for regulating the locations and strengths of recombination hotspots are not yet fully revealed. Most existing algorithms for estimating recombination rates from sequence polymorphism data can only output average recombination rates of a population, although there is evidence for the...
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