Identification of genomic mutations associated with clinical outcomes of induction chemotherapy in patients with head and neck squamous cell carcinoma.

doi:10.1007/s00432-015-2083-2

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Article

Identification of genomic mutations associated with clinical outcomes of induction chemotherapy in patients with head and neck squamous cell carcinoma.

Journal of cancer research and clinical oncology - 1 Apr 2016

Ock Chan-Young, Son Bongjun, Keam Bhumsuk, Lee Seung-Youn, Moon Jaewoo, Kwak Hwanjong, Kim Sehui, Kim Tae Min, Jeon Yoon Kyung, Kwon Seong Keun, Hah J Hun, Lee Se-Hoon, Kwon Tack-Kyun, Kim Dong-Wan, Wu Hong-Gyun, Sung Myung-Whun, Heo Dae Seog

Abstract excerpt

PURPOSE: We performed deep sequencing of target genes in head and neck squamous cell carcinoma (HNSCC) tumors to identify somatic mutations that are associated with induction chemotherapy (IC) response. METHODS: Patients who were diagnosed with HNSCC were retrospectively identified. Patients who were treated with IC were divided into two groups: good responders and poor responders by tumor response and...

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Identifiers

PMID: 26677030
DOI: 10.1007/s00432-015-2083-2

Genes

ATM
EGFR
FGFR2
FGFR3
MET
NOTCH3
PTEN
SUFU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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