Article
The relationship between Bordetella pertussis genotype and clinical severity in Australian children with pertussis.
The Journal of infection - 1 Feb 2016
Clarke Michelle, McIntyre Peter B, Blyth Christopher C, Wood Nick, Octavia Sophie, Sintchenko Vitali, Giles Lynne, Quinn Helen, Hill Verity, Hanly Gabrielle, Lan Ruiting, Marshall Helen S
Abstract excerpt
OBJECTIVES: Changes in circulating Bordetella pertussis genotypes, including a novel pertussis toxin promoter ptxP3 allele and absence of pertactin (Prn) antigen, have been reported from several countries but limited data on relative severity are available. We compared markers of disease severity in children with B. pertussis infection due to strains of differing genotype. METHODS: Culture confirmed cases...
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