Article
Severe pertussis infection in infants less than 6 months of age: Clinical manifestations and molecular characterization.
Human vaccines & immunotherapeutics - 4 May 2017
Stefanelli Paola, Buttinelli Gabriele, Vacca Paola, Tozzi Alberto E, Midulla Fabio, Carsetti Rita, Fedele Giorgio, Villani Alberto, Concato Carlo
Abstract excerpt
We conducted a study to determine the main traits of pertussis among unimmunized infants less than 6 months of age. From August 2012 to March 2015, 141 nasopharyngeal aspirates (NPAs) were collected from infants with respiratory symptoms attending 2 major hospitals in Rome. Clinical data were recorded and analyzed. Lab-confirmation was performed by culture and realtime PCR. B. pertussis virulence-associated genes...
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