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Article

Newly emerging clones of Bordetella pertussis carrying prn2 and ptxP3 alleles implicated in Australian pertussis epidemic in 2008-2010.

The Journal of infectious diseases - 15 Apr 2012

Octavia Sophie, Sintchenko Vitali, Gilbert Gwendolyn L, Lawrence Andrew, Keil Anthony D, Hogg Geoff, Lan Ruiting

Abstract excerpt

Australia is experiencing a prolonged epidemic of pertussis that began in 2008. A total of 194 Bordetella pertussis isolates collected from 2008 through 2010 were typed by single-nucleotide polymorphism (SNP) analysis, by multilocus variable number tandem repeats analysis, and by fim3, prn, and ptxP sequence analyses. Strains with 2 closely related SNP profiles carrying prn2 and ptxP3 from the recently emerged...

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PMID: 22416243
DOI: 10.1093/infdis/jis178

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