Article
Genetic analysis of Bordetella pertussis isolates from the 2008-2010 pertussis epidemic in Japan.
PloS one - 1 Jan 2013
Miyaji Yusuke, Otsuka Nao, Toyoizumi-Ajisaka Hiromi, Shibayama Keigo, Kamachi Kazunari
Abstract excerpt
A large pertussis epidemic occurred between 2008 and 2010 in Japan. To investigate epidemic strains, we analyzed 33 Bordetella pertussis isolates from the epidemic period by sequencing virulence-associated genes (fim3, ptxP, ptxA, and prn) and performing multilocus variable-number tandem repeat analysis (MLVA), and compared these results with those of 101 isolates from non-epidemic, earlier and later time...
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