Article
CDH1/E-cadherin and solid tumors. An updated gene-disease association analysis using bioinformatics tools.
Computational biology and chemistry - 1 Feb 2016
Abascal María Florencia, Besso María José, Rosso Marina, Mencucci María Victoria, Aparicio Evangelina, Szapiro Gala, Furlong Laura Inés, Vazquez-Levin Mónica Hebe
Abstract excerpt
Cancer is a group of diseases that causes millions of deaths worldwide. Among cancers, Solid Tumors (ST) stand-out due to their high incidence and mortality rates. Disruption of cell-cell adhesion is highly relevant during tumor progression. Epithelial-cadherin (protein: E-cadherin, gene: CDH1) is a key molecule in cell-cell adhesion and an abnormal expression or/and function(s) contributes to tumor progression...
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