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Recent advances in the role of atypical cadherin FAT1 in tumorigenesis (Review)

20 Dec 2024

Abstract excerpt

fat gene and encodes the protocadherin FAT1. FAT1 belongs to the cadherin superfamily, a group of full-length membrane proteins that contain cadherin-like repeats. In various types of human cancer, FAT1 is one of the most commonly mutated genes, and is considered to be an emerging cancer biomarker and a potential target for novel therapies. However, the biological functions of FAT1 and the precise downstream...

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PMID: 39776648
DOI: 10.3892/ol.2024.14856

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