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Article

Thyroid hormone action in metabolic regulation

1 May 2011

Abstract excerpt

Thyroid hormone plays pivotal roles in growth, differentiation, development and metabolic homeostasis via thyroid hormone receptors (TRs) by controlling the expression of TR target genes. The transcriptional activity of TRs is modulated by multiple factors including various TR isoforms, diverse thyroid hormone response elements, different heterodimeric partners, coregulators, and the cellular location of TRs. In...

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PMID: 21614672
DOI: 10.1007/s13238-011-1046-x

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