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Nuclear Receptor Coregulators and Human Disease

1 Aug 2007

Abstract excerpt

Nuclear receptor (NR) coregulators (coactivators and corepressors) are essential elements in regulating nuclear receptor-mediated transcription. In a little more than a decade since their discovery, these proteins have been studied mechanistically and reveal that the regulation of transcription is a highly controlled and complex process. Because of their central role in regulating NR-mediated transcription and in...

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PMID: 17609497
DOI: 10.1210/er.2007-0012

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