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Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

Diabetologia - 1 Jul 2016

Gan Wei, Walters Robin G, Holmes Michael V, Bragg Fiona, Millwood Iona Y, Banasik Karina, Chen Yiping, Du Huaidong, Iona Andri, Mahajan Anubha, Yang Ling, Bian Zheng, Guo Yu, Clarke Robert J, Li Liming, McCarthy Mark I, Chen Zhengming

Abstract excerpt

AIMS/HYPOTHESIS: Genome-wide association studies (GWAS) have discovered many risk variants for type 2 diabetes. However, estimates of the contributions of risk variants to type 2 diabetes predisposition are often based on highly selected case-control samples, and reliable estimates of population-level effect sizes are missing, especially in non-European populations. METHODS: The individual and cumulative effects...

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Identifiers

PMID: 27053236
DOI: 10.1007/s00125-016-3920-9
PMCID: PMC4901105

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CKB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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