Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation.

Genome medicine - 15 Dec 2015

Paul Dirk S, Jones Allison, Sellar Rob S, Mayor Neema P, Feber Andrew, Webster Amy P, Afonso Neuza, Sergeant Ruhena, Szydlo Richard M, Apperley Jane F, Widschwendter Martin, Mackinnon Stephen, Marsh Steven G E, Madrigal J Alejandro, Rakyan Vardhman K, Peggs Karl S, Beck Stephan

Abstract excerpt

BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for many hematological conditions. Acute graft-versus-host disease (aGVHD) is a prevalent immune-mediated complication following HSCT. Current diagnostic biomarkers that correlate with aGVHD severity, progression, and therapy response in graft recipients are insufficient. Here, we investigated whether epigenetic marks...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenomics
Share to Graft vs Host Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cell Transplantation

Share to HLA Antigens

Share to Siblings

Share to T-Lymphocytes

Share to Tissue Donors

Share to Transplantation Conditioning

Source

Open in PubMed Open full text

Identifiers

PMID: 26669438
DOI: 10.1186/s13073-015-0246-z
PMCID: PMC4681168

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation.PMID 26669438Read ↗

Review of Genetic Variation as a Predictive Biomarker for Chronic Graft-Versus-Host-Disease After Allogeneic Stem Cell Transplantation.Semantic proximity Read ↗

Non-HLA genomics: does it have a role in predicting haematopoietic stem cell transplantation outcome?Semantic proximity Read ↗

Defining genetic risk for graft-versus-host disease and mortality following allogeneic hematopoietic stem cell transplantation.Semantic proximity Read ↗

Genome-wide surveillance of mismatched alleles for graft-versus-host disease in stem cell transplantation.Semantic proximity Read ↗

Graft-versus-host disease biomarkers: omics and personalized medicine.Semantic proximity Read ↗

Systematic mining and quantification reveal the dominant contribution of non-HLA variations to acute graft-versus-host disease.Semantic proximity Read ↗

[Hematopoietic cell transplantation in the era of genome analysis].Semantic proximity Read ↗

Evolutionary divergence and expression of differential HLA alleles between donor and recipient influence acute GVHD onset after allogenetic HSCTSemantic proximity Read ↗

Cell-free DNA Profiling Informs Major Complications of Hematopoietic Cell TransplantationSemantic proximity Read ↗

Microsatellite scanning of the immunogenome associates MAPK14 and ELTD1 with graft-versus-host disease in hematopoietic stem cell transplantation.Semantic proximity Read ↗

Clinical potential of DNA methylation in organ transplantation.Semantic proximity Read ↗

A comprehensive model to predict severe acute graft-versus-host disease in acute leukemia patients after haploidentical hematopoietic stem cell transplantationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.