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Article

Structural Insights into the HIV-1 Minus-strand Strong-stop DNA.

The Journal of biological chemistry - 12 Feb 2016

Chen Yingying, Maskri Ouerdia, Chaminade Françoise, René Brigitte, Benkaroun Jessica, Godet Julien, Mély Yves, Mauffret Olivier, Fossé Philippe

Abstract excerpt

An essential step of human immunodeficiency virus type 1 (HIV-1) reverse transcription is the first strand transfer that requires base pairing of the R region at the 3'-end of the genomic RNA with the complementary r region at the 3'-end of minus-strand strong-stop DNA (ssDNA). HIV-1 nucleocapsid protein (NC) facilitates this annealing process. Determination of the ssDNA structure is needed to understand the...

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Share to Codon, Terminator
Share to DNA, Recombinant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Single-Stranded

Share to Electrophoretic Mobility Shift Assay

Share to gag Gene Products, Human Immunodeficiency Virus

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Share to Nucleic Acid Hybridization

Share to Nucleocapsid Proteins

Source

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Identifiers

PMID: 26668324
DOI: 10.1074/jbc.M115.708099
PMCID: PMC4751388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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