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Article

Specific interactions between HIV-1 nucleocapsid protein and the TAR element.

Journal of molecular biology - 20 May 2005

Kanevsky Igor, Chaminade Françoise, Ficheux Damien, Moumen Abdeladim, Gorelick Robert, Negroni Matteo, Darlix Jean-Luc, Fossé Philippe

Abstract excerpt

During retroviral reverse transcription, the minus-strand strong-stop DNA (ss-cDNA) is transferred to the 3' end of the genomic RNA and this requires the repeat (R) sequences present at both ends of the genome. In vitro, the human immunodeficiency virus type 1 (HIV-1) R sequence can promote DNA strand transfer when present in ectopic internal positions. Using HIV-1 model systems, the R sequences and nucleocapsid...

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Share to Capsid Proteins
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Single-Stranded

Share to gag Gene Products, Human Immunodeficiency Virus

Share to Gene Products, gag

Share to HIV Long Terminal Repeat

Share to Reverse Transcription

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Source

Identifiers

PMID: 15854644
DOI: 10.1016/j.jmb.2005.03.046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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