Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T Cell Fate at the Single-Cell Level

14 Dec 2015

Abstract excerpt

T cell responses display two key characteristics. First, a small population of epitope-specific naive T cells expands by several orders of magnitude. Second, the T cells within this proliferating population take on diverse functional and phenotypic properties that determine their ability to exert effector functions and contribute to T cell memory. Recent technological advances in lineage tracing allow us for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26666651
DOI: 10.1146/annurev-immunol-032414-112014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T Cell Fate at the Single-Cell LevelPMID 26666651Read ↗

In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells.Semantic proximity Read ↗

Unraveling the secrets of γδ T cells with single-cell biologySemantic proximity Read ↗

Clonally distinct differentiation trajectories shape CD8 <sup>+</sup> memory T cell heterogeneity after acute viral infections in humansSemantic proximity Read ↗

Germinal center-dependent and -independent memory B cells produced throughout the immune response.Semantic proximity Read ↗

Heterogeneity in the clonal T cell response. Implications for models of T cell activation and cytokine phenotype development.Semantic proximity Read ↗

Progenitor effects and unique transcriptomic signatures linked to differentiation phenotype in clonally expanded antigen-specific CD8 T memory stem cells.Semantic proximity Read ↗

Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity.Semantic proximity Read ↗

The who's who of T ‐cell differentiation: Human memory T ‐cell subsetsSemantic proximity Read ↗

Axes of heterogeneity in human tissue-resident memory T cells.Semantic proximity Read ↗

Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneitySemantic proximity Read ↗

The dynamic lives of T cells: new approaches and themes.Semantic proximity Read ↗

Identification of Nascent Memory CD8 T Cells and Modeling of Their Ontogeny.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.