Article
Transepidermal water loss measurement during infancy can predict the subsequent development of atopic dermatitis regardless of filaggrin mutations.
Allergology international : official journal of the Japanese Society of Allergology - 1 Jan 2016
Horimukai Kenta, Morita Kumiko, Narita Masami, Kondo Mai, Kabashima Shigenori, Inoue Eisuke, Sasaki Takashi, Niizeki Hironori, Saito Hirohisa, Matsumoto Kenji, Ohya Yukihiro
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is characterized by skin barrier dysfunction. Few studies have used noninvasive techniques to measure epidermis function in asymptomatic neonates. METHODS: Data of 116 infants from our previous randomized controlled study were analyzed. Skin barrier function was measured through transepidermal water loss (TEWL), stratum corneum hydration (SCH), and pH. The association between...
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