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Article

Atopic dermatitis and disease severity are the main risk factors for food sensitization in exclusively breastfed infants.

The Journal of investigative dermatology - 1 Feb 2014

Flohr Carsten, Perkin Michael, Logan Kirsty, Marrs Tom, Radulovic Suzana, Campbell Linda E, MacCallum Stephanie F, McLean W H Irwin, Lack Gideon

Abstract excerpt

Filaggrin (FLG) loss-of-function skin barrier gene mutations are associated with atopic dermatitis (AD) and transepidermal water loss (TEWL). We investigated whether FLG mutation inheritance, skin barrier impairment, and AD also predispose to allergic sensitization to foods. Six hundred and nineteen exclusively breastfed infants were recruited at 3 months of age and examined for AD and disease severity (SCORing...

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Source

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Identifiers

PMID: 23867897
DOI: 10.1038/jid.2013.298
PMCID: PMC3912359

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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