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Article

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

Cerebral cortex (New York, N.Y. : 1991) - 1 Jan 2015

Ha Seungshin, Stottmann Rolf W, Furley Andrew J, Beier David R

Abstract excerpt

Formation of a 6-layered cortical plate and axon tract patterning are key features of cerebral cortex development. Abnormalities of these processes may be the underlying cause for a range of functional disabilities seen in human neurodevelopmental disorders. To identify mouse mutants with defects in cortical lamination or corticofugal axon guidance, N-ethyl-N-nitrosourea (ENU) mutagenesis was performed using mice...

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PMID: 23968836
DOI: 10.1093/cercor/bht209
PMCID: PMC4259276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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