Article
Presenilin 1 in migration and morphogenesis in the central nervous system.
Development (Cambridge, England) - 1 Jul 2004
Louvi Angeliki, Sisodia Sangram S, Grove Elizabeth A
Abstract excerpt
Morphogenesis of the central nervous system relies in large part upon the correct migration of neuronal cells from birthplace to final position. Two general modes of migration govern CNS morphogenesis: radial, which is mostly glia-guided and topologically relatively simple; and tangential, which often involves complex movement of neurons in more than one direction. We describe the consequences of loss of function...
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