Article
Spectrum of mitochondrial genomic variation and associated clinical presentation of prostate cancer in South African men.
The Prostate - 1 Mar 2016
McCrow John P, Petersen Desiree C, Louw Melanie, Chan Eva K F, Harmeyer Katherine, Vecchiarelli Stefano, Lyons Ruth J, Bornman M S Riana, Hayes Vanessa M
Abstract excerpt
BACKGROUND: Prostate cancer incidence and mortality rates are significantly increased in African-American men, but limited studies have been performed within Sub-Saharan African populations. As mitochondria control energy metabolism and apoptosis we speculate that somatic mutations within mitochondrial genomes are candidate drivers of aggressive prostate carcinogenesis. METHODS: We used matched blood and prostate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.