Article
A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men.
EBioMedicine - 1 Dec 2015
Petrovics Gyorgy, Li Hua, Stümpel Tanja, Tan Shyh-Han, Young Denise, Katta Shilpa, Li Qiyuan, Ying Kai, Klocke Bernward, Ravindranath Lakshmi, Kohaar Indu, Chen Yongmei, Ribli Dezső, Grote Korbinian, Zou Hua, Cheng Joseph, Dalgard Clifton L, Zhang Shimin, Csabai István, Kagan Jacob, Takeda David, Loda Massimo, Srivastava Sudhir, Scherf Matthias, Seifert Martin, Gaiser Timo, McLeod David G, Szallasi Zoltan, Ebner Reinhard, Werner Thomas, Sesterhenn Isabell A, Freedman Matthew, Dobi Albert, Srivastava Shiv
Abstract excerpt
Evaluation of cancer genomes in global context is of great interest in light of changing ethnic distribution of the world population. We focused our study on men of African ancestry because of their disproportionately higher rate of prostate cancer (CaP) incidence and mortality. We present a systematic whole genome analyses, revealing alterations that differentiate African American (AA) and Caucasian American...
Topics
Join the communities discussing this publication.