Critical roles for murine Reck in the regulation of vascular patterning and stabilization.

doi:10.1038/srep17860

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Article

Critical roles for murine Reck in the regulation of vascular patterning and stabilization.

Scientific reports - 11 Dec 2015

de Almeida Glícia Maria, Yamamoto Mako, Morioka Yoko, Ogawa Shuichiro, Matsuzaki Tomoko, Noda Makoto

Abstract excerpt

Extracellular matrix (ECM) is known to play several important roles in vascular development, although the molecular mechanisms behind these remain largely unknown. RECK, a tumor suppressor downregulated in a wide variety of cancers, encodes a membrane-anchored matrix-metalloproteinase-regulator. Mice lacking functional Reck die in utero, demonstrating its importance for mammalian embryogenesis; however, the...

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Identifiers

PMID: 26658478
DOI: 10.1038/srep17860
PMCID: PMC4675993

Genes

RECK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.