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Article

Matrix metalloproteinase inhibitor reversion‐inducing cysteine‐rich protein with Kazal motifs

19 May 2003

Abstract excerpt

BACKGROUND: The recently described reversion-inducing cysteine-rich protein with Kazal motifs (RECK) inhibits membrane Type 1 matrix metalloproteinase (MMP-14), MMP-2, and MMP-9 secretion and enzymatic activity. Its expression is essential for normal vasculogenesis. Down-regulation of RECK has been implicated in tumor angiogenesis and progression. METHODS: The authors assessed the prognostic value of RECK...

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PMID: 12767082
DOI: 10.1002/cncr.11395

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