Article
Generation and characterization of a mouse line carrying Reck-CreERT2 knock-in allele.
Genesis (New York, N.Y. : 2000) - 1 Apr 2018
Matsuzaki Tomoko, Wang Huan, Imamura Yukio, Kondo Shunya, Ogawa Shuichiro, Noda Makoto
Abstract excerpt
Reck encodes a membrane-anchored glycoprotein implicated in the regulation of extracellular metalloproteinases, Notch-signaling, and Wnt7-signaling and shown to play critical roles in embryogenesis and tumor suppression. Precise mechanisms of its actions in vivo, however, remain largely unknown. By homologous recombination, we generated a new Reck allele, ReckCreERT2 (MGI symbol: Reck<tm3.1(cre/ERT2)Noda>). This...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.