Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental biology: vasculogenesis is a wreck without RECK.

Current biology : CB - 19 Mar 2002

Welm Bryan, Mott Joni, Werb Zena

Abstract excerpt

The unique membrane-associated inhibitor of matrix metalloproteinases, RECK, is required for vascular maturation during embryogenesis. The phenotype of a loss of function mutation of RECK shows the importance of pericellular proteolysis in development.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Tissue Inhibitor of Metalloproteinase-2
Share to Blood Vessels
Share to Endothelium, Vascular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Glycoproteins

Share to GPI-Linked Proteins

Share to Matrix Metalloproteinases

Share to Membrane Glycoproteins

Source

Identifiers

PMID: 11909548
DOI: 10.1016/s0960-9822(02)00752-2

Genes

RECK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11909548-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental biology: vasculogenesis is a wreck without RECK.PMID 11909548Read ↗

Critical roles for murine Reck in the regulation of vascular patterning and stabilization.Semantic proximity Read ↗

The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis.Semantic proximity Read ↗

Dual effects of the membrane-anchored MMP regulator RECK on chondrogenic differentiation of ATDC5 cells.Semantic proximity Read ↗

RECK, a novel matrix metalloproteinase regulator.Semantic proximity Read ↗

RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity.Semantic proximity Read ↗

The metalloproteinase inhibitor Reck is essential for zebrafish DRG development.Semantic proximity Read ↗

Reck enables cerebrovascular development by promoting canonical Wnt signaling.Semantic proximity Read ↗

Generation and characterization of a mouse line carrying Reck-CreERT2 knock-in allele.Semantic proximity Read ↗

Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFDSemantic proximity Read ↗

Matrix metalloproteinase inhibitor reversion‐inducing cysteine‐rich protein with Kazal motifsSemantic proximity Read ↗

ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis.Semantic proximity Read ↗

An essential role for ectodomain shedding in mammalian development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.