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Article

Painful diabetic neuropathy is associated with accelerated epigenetic aging

23 Jan 2025

Abstract excerpt

About one out of two diabetic patients develop diabetic neuropathy (DN), of these 20% experience neuropathic pain (NP) leading to individual, social, and health-economic burden. Risk factors for NP are largely unknown; however, premature aging was recently associated with several chronic pain disorders. DNA methylation-based biological age (DNAm) is associated with disease risk, morbidity, and mortality in...

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Dietary Effects on Health
Epigenetics and DNA Methylation
Pain Management and Opioid Use

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39847262
DOI: 10.1007/s11357-025-01516-w

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