Article

Human immune phenotyping reveals accelerated aging in type 1 diabetes

2023-02-26

Abstract excerpt

The composition of immune cells in peripheral blood is dramatically remodeled throughout the human lifespan, as environmental exposures shape the proportion and phenotype of cellular subsets. These dynamic shifts complicate efforts to identify disease-associated immune signatures in type 1 diabetes (T1D), which is variable in age of onset and rate of β-cell decline. Herein, we conducted standardized flow cytometri...

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Literature Corpus work: 7b77bff8-cc26-5cb3-a4ae-90321ab2c14c
DOI: 10.1101/2023.02.24.529902

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