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Epigenetic age oscillates during the day

18 Apr 2024

Abstract excerpt

Since their introduction, epigenetic clocks have been extensively used in aging, human disease, and rejuvenation studies. In this article, we report an intriguing pattern: epigenetic age predictions display a 24-h periodicity. We tested a circadian blood sample collection using 17 epigenetic clocks addressing different aspects of aging. Thirteen clocks exhibited significant oscillations with the youngest and...

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PMID: 38638005
DOI: 10.1111/acel.14170

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