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Article

Signal Transduction: Gain of Activin Turns Muscle into Bone.

Current biology : CB - 7 Dec 2015

Sanchez-Duffhues Gonzalo, Fotsis Theodore, ten Dijke Peter

Abstract excerpt

Recent data provide an unexpected twist in our understanding of the pathogenesis of fibrodysplasia ossificans progressiva. Surprisingly, the causative amino acid mutation of the BMP receptor responds to activin, thereby turning soft tissues into bone.

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Identifiers

PMID: 26654374
DOI: 10.1016/j.cub.2015.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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