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Article

Diabetic Phenotypes and Late-Life Dementia Risk: A Mechanism-specific Mendelian Randomization Study.

Alzheimer disease and associated disorders - 1 Jan 2000

Walter Stefan, Marden Jessica R, Kubzansky Laura D, Mayeda Elizabeth R, Crane Paul K, Chang Shun-Chiao, Cornelis Marilyn, Rehkopf David H, Mukherjee Shubhabrata, Glymour M Maria

Abstract excerpt

BACKGROUND: Mendelian Randomization (MR) studies have reported that type 2 diabetes (T2D) was not associated with Alzheimer disease (AD). We adopted a modified, mechanism-specific MR design to explore this surprising result. METHODS: Using inverse-variance weighted MR analysis, we evaluated the association between T2D and AD using data from 39 single nucleotide polymorphisms (SNPs) significantly associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26650880
DOI: 10.1097/WAD.0000000000000128
PMCID: PMC4879683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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