Article
Analysis of human papillomavirus 16 variants and risk for cervical cancer in Chinese population.
Virology - 15 Jan 2016
Hang Dong, Yin Yin, Han Jing, Jiang Jie, Ma Hongxqia, Xie Shuanghua, Feng Xiaoshuang, Zhang Kai, Hu Zhibin, Shen Hongbing, Clifford Gary M, Dai Min, Li Ni
Abstract excerpt
HPV16 is the most carcinogenic HPV type, but only a minority of HPV16 infections progress to cancer. Intratype genetic variants of HPV16 have been suggested to confer differential carcinogenicity. To investigate risk implications of HPV16 variants among Chinese women, a case-control study was conducted with 298 cervical cancer patients and 85 controls (all HPV16-positive). HPV16 isolates were predominantly of the...
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