Article
Whole-Genome Analysis of Human Papillomavirus Types 16, 18, and 58 Isolated from Cervical Precancer and Cancer Samples in Chinese Women.
Scientific reports - 21 Mar 2017
Liu Ying, Pan Yaqi, Gao Weijiao, Ke Yang, Lu Zheming
Abstract excerpt
Human papillomavirus (HPV) types 16, 18 and 58 are ranked the top three high-risk HPV types for cervical intraepithelial neoplasia (CIN) and invasive carcinoma. We aimed to evaluate the diversity of HPV16, HPV18, and HPV58 genetic variants by HPV capture technology combined with next generation sequencing. 295, 73, and 148 variations were observed in 51 HPV16, 7 HPV18, and 11 HPV58 genomes, respectively. HPV16...
Topics
- Asian People
- Female
- Genetic Variation
- Genome, Viral
- Genotype
- High-Throughput Nucleotide Sequencing
- Humans
- Papillomaviridae
- Papillomavirus Infections
- Phylogeny
- Precancerous Conditions
