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Article

Analysis of genetic variation in human papillomavirus type 16 E1 and E2 in women with cervical infection in Xinjiang, China.

BMC medical genomics - 12 Nov 2021

Wang Luyue, Wang Fang, Fu Shaowei, Zhang Chunhe, Zhe Xiangyi, Li Hongtao, Li Dongmei, Shao Renfu, Pan Zemin

Abstract excerpt

BACKGROUND: Xinjiang is one of the regions with a high incidence of cervical cancer, and the genetic variation of human papillomavirus may increase its ability to infect the human body and enhance virus-mediated immune escape ability. METHODS: Sanger sequencing of the HPV16 genome from 165 samples positive for HPV16 infection and phylogenetic analysis of the E1 and E2 genes revealed the gene polymorphism of HPV16...

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Identifiers

PMID: 34772425
DOI: 10.1186/s12920-021-01120-9
PMCID: PMC8590209

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