Article
Oestradiol metabolism and androgen receptor genotypes are associated with right ventricular function.
The European respiratory journal - 1 Feb 2016
Ventetuolo Corey E, Mitra Nandita, Wan Fei, Manichaikul Ani, Barr R Graham, Johnson Craig, Bluemke David A, Lima Joao A C, Tandri Hari, Ouyang Pamela, Kawut Steven M
Abstract excerpt
Sex hormones are linked to right ventricular (RV) function, but the relationship between genetic variation in these pathways and RV function is unknown.We performed a cross-sectional study of 2761 genotyped adults without cardiovascular disease. The relationships between RV measures and single nucleotide polymorphisms (SNPs) in 10 candidate genes were assessed. Urinary oestradiol (E2) metabolites produced by...
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