Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dystrophic phenotype improvement in the diaphragm muscle of mdx mice by diacerhein.

PloS one - 1 Jan 2017

Mâncio Rafael Dias, Hermes Túlio de Almeida, Macedo Aline Barbosa, Mizobuti Daniela Sayuri, Rupcic Ian Feller, Minatel Elaine

Abstract excerpt

Chronic inflammation and oxidative stress are striking features of Duchenne muscular dystrophy disease. Diacerhein is an anthraquinone, which exhibits anti-inflammatory and antioxidant properties. Based on their actions, the present study evaluated the effects of diacerhein against myonecrosis, oxidative stress and inflammatory response in the diaphragm muscle of mdx mice and compared these results to current...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthraquinones
Share to Diaphragm
Share to Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred mdx

Share to Muscle, Skeletal

Share to Muscular Dystrophy, Duchenne

Share to Necrosis

Share to Oxidative Stress

Source

Open in PubMed Open full text

Identifiers

PMID: 28787441
DOI: 10.1371/journal.pone.0182449
PMCID: PMC5546703

Genes

DMD
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dystrophic phenotype improvement in the diaphragm muscle of mdx mice by diacerhein.PMID 28787441Read ↗

Enhancement of Prednisolone efficacy and safety in Duchenne muscular dystrophy via neutrophil elastase inhibitionSemantic proximity Read ↗

Beneficial cilostazol therapeutic effects in mdx dystrophic skeletal muscle.Semantic proximity Read ↗

Co-administration of deflazacort and doxycycline: a potential pharmacotherapy for Duchenne muscular dystrophy.Semantic proximity Read ↗

Amplification of proinflammatory phenotype, damage, and weakness by oxidative stress in the diaphragm muscle of mdx mice.Semantic proximity Read ↗

Dimethyl fumarate modulates the Duchenne muscular dystrophy disease program following short-term treatment in <i>mdx</i> miceSemantic proximity Read ↗

Evaluation of pro-regenerative and anti-inflammatory effects of isolecanoric acid in the muscle: Potential treatment of Duchenne Muscular DystrophySemantic proximity Read ↗

Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne.Semantic proximity Read ↗

Nutritional intervention with cyanidin hinders the progression of muscular dystrophy.Semantic proximity Read ↗

Natural products, PGC-1 , and Duchenne muscular dystrophySemantic proximity Read ↗

Oxidative stress in Duchenne muscular dystrophy: focus on the NRF2 redox pathwaySemantic proximity Read ↗

Targeting Nrf2 for the treatment of Duchenne Muscular DystrophySemantic proximity Read ↗

Flavonoids and Omega3 Prevent Muscle and Cardiac Damage in Duchenne Muscular Dystrophy Animal Model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.