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Article

Doxycycline ameliorates the dystrophic phenotype of skeletal and cardiac muscles in mdx mice.

Muscle & nerve - 1 Sept 2012

Pereira Juliano Alves, Taniguti Ana Paula Tiemi, Matsumura Cíntia, Marques Maria Julia, Neto Humberto Santo

Abstract excerpt

INTRODUCTION: We examined whether doxycycline, an antibiotic member of the tetracycline family, improves the histopathology and muscle function in mdx mice, the experimental model of DMD. METHODS: Doxycycline was administered for 36 days (starting on postnatal day 0) and for 9 months (starting at...

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Source

Identifiers

PMID: 22907231
DOI: 10.1002/mus.23331

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22907231-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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