Article
Genetic Variations in Key MicroRNAs are Associated With the Survival of Nonsmall Cell Lung Cancer.
Medicine - 1 Nov 2015
Wu Shuangshuang, Shen Wei, Pan Yun, Zhu Meng, Xie Kaipeng, Geng Liguo, Wang Yuzhuo, Liang Yan, Xu Jiali, Cao Songyu, Xu Wei, Chen Bo, Hu Zhibin, Ma Hongxia, Wu Jianqing, Shen Hongbing
Abstract excerpt
MicroRNAs (miRNAs) are a class of small, noncoding RNA molecules involved in carcinogenesis. It has been identified that genetic variations in miRNAs contribute to cancer risk, prognosis, and survival. In the present study, we investigated whether single nucleotide polymorphisms (SNPs) of several key miRNAs (miR-184, miR-218, and miR-124) were associated with the prognosis of nonsmall cell lung cancer (NSCLC) in...
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